Development Plan

NanoBio's NB-00X product formulation has demonstrated fungicidal activity against all dermatophytes tested to date, and has shown a remarkable safety profile in numerous human and animal studies.  The company is currently testing NB-00X's activity against the dermatophytes most commonly indicated in tinea capitis, and expects to announce plans in 2008 to begin Phase 2 testing of the product.

About Tinea capitis

Tinea capitis is a disease caused by superficial fungal infection of the skin of the scalp, eyebrows, and eyelashes, with a propensity for attacking hair shafts and follicles. The disease is considered to be a form of superficial mycosis or dermatophytosis.  Several synonyms are used, including ringworm of the scalp and tinea tonsurans. In the United States and other regions of the world, the incidence of tinea capitis is increasing. 

There are currently no effective topicals available for the treatment of tinea capitis.

Systemic administration of itraconazole and terbinafine are used most commonly for the treatment of tinea capitis.  The potential for side effects with systemic antifungals is a special concern considering that the majority of patients are preadolescent children.