Strategic Alliances

In December 2009, NanoBio Corporation and GlaxoSmithKline, plc (GSK) announced an exclusive licensing agreement in the United States and Canada for the over-the-counter (OTC) use of NB-001, a novel, patented compound representing the next advance in the treatment of herpes labialis (cold sores). Under the terms of the agreement, NanoBio received an up-front payment of $14.5 million, and is eligible to receive additional milestone payments of up to $40 million plus royalties on future sales.

GSK's market leading Abreva product is the only OTC therapy approved by the US Food & Drug Administration to shorten cold sore healing time. GSK plans to build on its Abreva brand with the future launch of NB-001.  GSK Consumer Healthcare is one of the world’s largest over-the-counter consumer healthcare products companies with more than 30 well-known OTC brands.

In December 2011, NanoBio Corporation announced a preclinical collaboration with Merck & Co., Inc., focused on the development of a vaccine for Respiratory Syncytial Virus (RSV). The studies will evaluate the combination of Merck’s proprietary RSV antigen with NanoBio’s NanoStat® adjuvant technology, for use as an intranasal vaccine. As part of the agreement, Merck has the option to negotiate a license to the NanoStat® adjuvant for development of a commercial RSV vaccine.

In November 2010, NanoBio Corporation announced that it received a $6M grant from the Bill & Melinda Gates Foundation to support the development of a safe and effective intranasal vaccine for Respiratory Syncytial Virus (RSV). The grant covers a two year research period.

In October 2009, the University of Michigan and NanoBio Corporation announced a $9.3 million contract award for vaccine adjuvant research from the National Institute of Allergy and Infectious Diseases, a Division of The National Institute of Health. NanoBio and the University will collaborate over the 5 year research period to support efforts aimed at developing nanoemulsion-based mucosal vaccine adjuvants for a wide variety of antigens.