Anti-infectives:

• Nanoemulsion Topical Efficacy in a Herpes Simplex Type 1 Murine Ear Lesion Model. NanoBio® sponsored study: 

• A novel surfactant nanoemulsion with broad-spectrum sporicidal activity against Bacillus Species.Hamouda T, Hayes M, Cao Z, Tonda R, Johnson K, Wright DC, Brisker J, Baker JR Jr (1999). The Journal of Infectious Diseases 180:1939-49.

• Antimicrobial mechanism of action of surfactant lipid preparations in enteric Gram-negative bacilli.  Hamouda T, Baker JR Jr (2000) Journal of Applied Microbiology 89:397-403.  Download PDF (2100K) 

• A novel surfactant nanoemulsion with a unique non-irritant topical antimicrobial activity against bacteria, enveloped viruses and fungi.Hamouda T, Myc A, Donovan B, Shih A, Reuter J, Baker JR Jr (2001). Microbiological Research 156: 1-7.

• The fungicidal activity of novel nanoemulsion (X8W60PC) against clinically important yeast and filamentous fungi. Myc A, Vanhecke T, Landers JJ, Hamouda T, Baker Jr. JR (2001). Mycopathologia 155: 195-201, (2002).

Vaccines/Adjuvants:

• Prevention of murine influenza A virus pneumonitis by surfactant nanoemulsions. Donovan BW, Reuter JD, Cao Z, Myc A, Johnson KJ, and Baker Jr. Antiviral Chemistry & Chemotherapy; 11: 41-49, (2000). 

• Development of immune response that protects mice from viral pneumonitis after a single intranasal immunization with influenza A virus and nanoemulsion. Myc A, Kukowska-Latallo JF, Bielinska AU, Cao P, Myc PP, Janczak K, Sturm TR, Grabinski MS, Landers JJ, Young K, Chang J, Hamouda T, Olszewski MA, Baker, Jr JR. Vaccine; 21: 3801-3814, (2003).

• Mucosal Immunization with a Novel Nanoemulsion-Based Recombinant Anthrax Protective Antigen Vaccine Protects against Bacillus anthracis Spore Challenge. Anna U. Bielinska,1 Katarzyna W. Janczak,1 Jeffrey J. Landers,1 Paul Makidon,1 Laurie E. Sower,2 Johnny W. Peterson,2 and James R. Baker, Jr.Infection and Immunity, p. 4020–4029 Vol. 75, No. 8, (2007).